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Psilocybin

shroom news
Research / In The News, Mental Health, Psilocybin

A single dose of psilocybin may be associated with antidepressant effects. 

A single dose of psilocybin, a psychedelic and serotonin 2A receptor (5-HT2AR) agonist, may be associated with antidepressant effects. The mechanism behind its antidepressive action is unknown but could be linked to increased synaptogenesis and down-regulation of cerebral 5-HT2AR. Here, we investigate if a single psychedelic dose of psilocybin changes synaptic vesicle protein 2A (SV2A) and 5-HT2AR density in the pig brain. Twenty-four awake pigs received either 0.08 mg/kg psilocybin […]

A single dose of psilocybin may be associated with antidepressant effects.  Read Post »

Restrictions on Psilocybin ‘Magic Mushrooms’ Are Easing as Research Ramps Up
Research / In The News, Psilocybin

Restrictions on Psilocybin ‘Magic Mushrooms’ Are Easing as Research Ramps Up

Excerpt: Magic mushrooms are undergoing a transformation from illicit recreational drug to promising mental health treatment. Numerous studies have reported positive findings using psilocybin—the mushrooms’ main psychoactive compound—for treating depression as well as smoking and alcohol addiction, and for reducing anxiety in the terminally ill. Ongoing and planned studies are testing the drug for conditions that include opioid dependence, PTSD and anorexia nervosa. Article Link: Scientific American Date: November 4,

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Psychedelic Treatment with Psilocybin Relieves Major Depression, Study Shows
Research / In The News, Mental Health, Psilocybin

Psychedelic Treatment with Psilocybin Relieves Major Depression, Study Shows

Excerpt: In a small study of adults with major depression, Johns Hopkins Medicine researchers report that two doses of the psychedelic substance psilocybin, given with supportive psychotherapy, produced rapid and large reductions in depressive symptoms, with most participants showing improvement and half of study participants achieving remission through the four-week follow-up. Article Link: The Johns Hopkins University, The Johns Hopkins Hospital

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shroom news
Research / In The News, Psilocybin

Neuroscientists: This Is How Shrooms Break Down Your Sense of Self

Many people who take psychedelic drugs like shrooms or LSD describe one aspect of the experience as a “compromised self of ‘self,’” or a breaking down of the familiar feeling of a boundary between yourself and the universe. It can be a moment of profound breakthrough, or a horrible experience — a “bad trip” — that turns you off the substance forever. Now, neuroscientists from the Netherlands’ Maastricht University think they’ve uncovered

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